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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
23.03
Human Site:
T545
Identified Species:
38.97
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
T545
P
G
S
E
A
R
T
T
G
D
I
S
V
E
K
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
T772
P
G
S
E
A
R
T
T
G
D
I
S
V
E
K
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S597
C
P
R
T
P
T
T
S
R
E
A
S
D
P
A
Dog
Lupus familis
XP_542019
1076
118222
T678
P
G
P
E
V
R
S
T
G
D
I
S
V
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
T548
P
G
A
E
I
R
H
T
G
D
I
S
M
E
K
Rat
Rattus norvegicus
Q63433
946
104449
T548
P
G
S
E
I
R
S
T
G
D
I
S
M
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
A585
R
T
P
A
H
A
P
A
A
R
V
A
S
A
P
Chicken
Gallus gallus
XP_422357
1013
114806
T569
P
Q
A
P
V
P
A
T
V
P
V
V
D
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
T554
P
N
A
H
T
L
Q
T
G
E
I
S
V
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Y271
T
T
T
M
T
S
G
Y
N
S
S
S
C
M
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
E344
I
S
G
S
S
N
S
E
N
S
G
Y
L
Q
Q
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
G405
P
S
K
D
K
M
G
G
V
E
V
Q
D
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
K730
D
H
I
D
L
E
T
K
Q
K
L
D
W
E
N
Red Bread Mold
Neurospora crassa
P87253
1142
127954
R703
G
G
S
P
G
Y
G
R
P
D
S
R
D
D
E
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
13.3
80
N.A.
73.3
80
N.A.
0
13.3
N.A.
53.3
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
26.6
86.6
N.A.
86.6
93.3
N.A.
13.3
33.3
N.A.
66.6
N.A.
13.3
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
8
15
8
8
8
8
0
8
8
0
22
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
0
15
0
0
0
0
0
43
0
8
29
8
0
% D
% Glu:
0
0
0
36
0
8
0
8
0
22
0
0
0
50
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
43
8
0
8
0
22
8
43
0
8
0
0
0
0
% G
% His:
0
8
0
8
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
15
0
0
0
0
0
43
0
0
0
0
% I
% Lys:
0
0
8
0
8
0
0
8
0
8
0
0
0
0
43
% K
% Leu:
0
0
0
0
8
8
0
0
0
0
8
0
8
0
8
% L
% Met:
0
0
0
8
0
8
0
0
0
0
0
0
15
8
0
% M
% Asn:
0
8
0
0
0
8
0
0
15
0
0
0
0
0
8
% N
% Pro:
58
8
15
15
8
8
8
0
8
8
0
0
0
8
8
% P
% Gln:
0
8
0
0
0
0
8
0
8
0
0
8
0
8
8
% Q
% Arg:
8
0
8
0
0
36
0
8
8
8
0
8
0
0
8
% R
% Ser:
0
15
29
8
8
8
22
8
0
15
15
58
8
0
8
% S
% Thr:
8
15
8
8
15
8
29
50
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
15
0
0
0
15
0
22
8
29
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _